Winter Storm Nacio took aim at the Ohio Valley and mid-Atlantic on Tuesday, dumping more than a half-foot of snow in some areas.

The snow began in earnest Tuesday morning, and roads quickly became hazardous during the morning drive in several cities. The heavy snow may have also resulted in a fatal accident in Pennsylvania. Air travel was impacted as well; many of the nearly 250 canceled domestic flights , according to FlightAware data.

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Here are the latest impacts from the areas affected by Nacio.

Pennsylvania

One woman was killed in an accident involvingin Monroe Township at about 12:45 p.m. Tuesday afternoon, according to WGAL.com. The woman was identified as Sadie Danielle Wells, 20, , according to the Salt Lake Tribune.

The three other passengers in the car were taken to Hershey Medical Center, one of which was listed in serious condition, the report added. Of the 32 students on the bus, one was taken to the hospital with a non-life threatening injury, while the rest suffered no major injuries, the Cumberland Valley School District said in a statement. The students being transportedwere fromCumberland Valley High School and Eagle View Middle School.

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"Areas of heavy snow caused difficult travel conditions in the vicinity of the crash on Tuesday, with significantly reduced visibility," said weather.com meteorologist . "About 5 inches of snow had fallen as of late Tuesday afternoon, most of that in a short span around midday."

Anin Schuylkill County, according toWBRE in Pennsylvania. The accident has shut down the highway from exits 112-107 on the southbound side. No injuries were reported.

Ohio

More than a half-foot of snow fell from Nacio in parts of the Buckeye State Tuesday morning, and crews were working feverishly to keep roads cleared of snow so travel could continue. Level 1 snow emergencies were declared in Butler and Hamilton counties, , Cincinnati.com said.

"Even a little snow can cause big headaches," Cheryl Parker, AAA spokesperson, told Cincinnati.com. "With snow accumulation and below-freezing temperatures, some roads will certainly be slick."

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Most schools in central Ohio following the snowstorm, according to the Columbus Dispatch.

Washington D.C.

Federal offices remained open Tuesday as Nacio arrived in the Nation's Capital, the Associated Press reported. However, federal employees have been told that they could take unscheduled leave or telework, according to the U.S. Office of Personnel Management.

Road crews worked overnight Monday to prepare the district's roads for the snow in hopes that they wouldn't see a repeat disaster like the one during the evening rush hour on Jan. 20.

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"We don't want to get caught by surprise in case ," Chris Geldart, director of the D.C. Homeland Security and Emergency Management Agency, told NBC Washington.

Public schools held classes as scheduled in the district on Tuesday and Wednesday.

Maryland

Baltimore City Schools were closed Tuesday as the state prepared for Nacio's snowy blast, and on Wednesday, the district opened after a 2-hour delay. In extreme western parts of Maryland, up to 8 inches of snow fell from this storm, though Baltimore received far less.

Baltimore/Washington International Airport led the nation in flight cancelations Tuesday morning. According to FlightAware, more than three dozen flights had been canceled into and out of the airportby 9 a.m. EST Tuesday morning.

WBAL-TV in the Baltimore area.

Virginia

The highest snow total from Winter Storm Nacio– 8.2 inches near Norton– fell in the Commonwealth. Where the heaviest snowfall totals were reported, ice- and snow-covered roadways , according to the Virginia Department of Transportation.

Tennessee

Parts of the Volunteer State received as much as 7 inches of snow from this quick blast of wintry weather, but it was the ice on state roadways that especially concerned officials Tuesday. Around the Nashville area, authorities Tuesday morning, according to the Tennessean.

Many school districts will remain closed Wednesday in Middle Tennessee; for a complete list, .

Alabama

Near the Tennessee border, officials had to close Interstate 65 because of accidents Tuesday morning, state troopers told the AP. After a light accumulation of snowfall turned to slush on roads in northern Alabama, travel became treacherous.

As a result of the wintry weather, some schools in the area delayed opening or closed early Tuesday, the AP also said. Officials opened warming centers Tuesday night in several public buildings for anyone who needed them.

"Of course, the concern tonight would be if we did have any moisture left on the roadways, we may have some patchy black ice," Madison County Emergency Management Agency Officer Scott Worsham told the AP. "We're just waiting to see if that materializes — hopefully not."

Georgia

Several school districts planned to close early Tuesday afternoon due to the wintry conditions. Several schools districts as some North Georgia roads remained icy, WXIA-TV reported.

The state reported modest snow totals– 2 inches or less, according to the National Weather Service.

West Decatur Elementary students, Kelvin and Flowah Harris arrive at school in Decatur, Ala., through a shower of snowflakes, Tuesday, Feb. 9, 2016. (John Godbey/The Decatur Daily via AP)